Prescription & Illicit Stimulant Addiction

Stimulants—even those that have medicinal benefits—can be dangerous and addictive when misused.1-3 This page will define stimulants and their characteristics, cover the risks of stimulant misuse, and explain how treatment for stimulant addiction works.
What Are Stimulants?

What Are Stimulant Drugs?

Stimulant pills on table

Stimulants are drugs have an accelerating effect on the body’s systems, increasing heart rate, breathing, blood flow, and other physical processes.1,4 Stimulants generally increase alertness, attention, and energy.1, 4 Prescription stimulants are used to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy.1

Common prescription stimulants include:1

  • Ritalin (methylphenidate).
  • Dexedrine (dextroamphetamine).
  • Adderall (dextroamphetamine/amphetamine).

Common illicit stimulants include:4,5

  • Methamphetamine.
  • Cocaine/crack.
  • Cathinones:
    • Khat (plant with naturally occurring cathinones).
    • Synthetic cathinones manufactured in labs (“bath salts”).

Both legal and illegal stimulants increase dopamine, norepinephrine, and serotonin activity in the brain and have the potential to produce a euphoric high. 1-3 Euphoria combined with other desirable effects such as increased wakefulness, sociability, and decreased appetite contribute to the abuse potential of these drugs.6

How Does Prescription Stimulant Abuse Start?

People that are prescribed stimulants may begin misusing them for their pleasurable effects. Others may acquire prescription stimulants illicitly (without a prescription), such as by taking a friend’s unwanted medication or purchasing it illegally.1

Nonmedical use of ADHD medications (e.g., Adderall) is especially problematic among adolescents and young adults. According to the Substance Abuse and Mental Health Services Administration (SAMHSA), it is estimated that anywhere from 5to 35% of U.S. college students report misusing Rx stimulants to improve their academic performance, control their weight, or to get high.7,8

Long-term use of prescription stimulants may cause someone to develop a tolerance, meaning they will need stronger or more frequent doses to feel the drug’s effects. Many serious negative health effects (discussed below) can occur when someone takes excessive and increasing doses of stimulants, particularly over long periods of time.1

Over time and with chronic use, dependence may also develop. A stimulant-dependent person will need to keep taking a stimulant to avoid withdrawal. Tolerance and dependence are both criteria used to diagnose a stimulant use disorder, the clinical term for stimulant addiction. Someone taking stimulants prescribed by a physician may also develop tolerance and dependence; however, since these adaptations are expected and managed by a doctor, they are not considered as criteria met during an evaluation for a stimulant use disorder.” 1

Health Effects

Short-Term Stimulant Effects

In addition to the primary effects of increased energy, wakefulness, or attention, stimulants have several side effects, some of which are potentially lethal. These side effects of stimulant use may include:1-3,5

  • Increased blood pressure and decreased blood flow.
  • Increased heart rate.
  • Irregular heartbeat.
  • Loss of appetite.
  • Involuntary jaw clenching and teeth grinding.
  • Elevated blood sugar.
  • Increased body temperature.
  • Seizures.
  • Heart failure.

What Are the Long-Term Effects of Stimulants?

Chronic use of stimulants can also cause: 1- 3,5,8-9

  • Unhealthy weight loss.
  • Anxiety.
  • Insomnia.
  • Dental problems.
  • Impaired sexual function.
  • Chest pain, cardiovascular dysfunction, and heart problems.
  • Cognitive impairment, including problems with learning and memory.
  • Symptoms of psychosis, including paranoia, delusions, and hallucinations (visual, auditory and tactile).

People who snort stimulants risk damage to nasal membranes including perforation of the bone and cartilage (i.e., nasal septum) that separates the nostrils. Smoking crack cocaine can worsen asthma and damage the lungs.10 Smoking meth has been associated with an increased risk of lung infection (e.g., pneumonia) as well as acute respiratory failure.11 People that inject stimulants are at increased risk of contracting HIV or hepatitis as well as other infections through the use of shared needles and other injection equipment.2,3

Signs of Abuse

Signs of Prescription and Illicit Stimulant Misuse

Any use of an illegal stimulant, such as cocaine or meth, constitutes drug abuse. 12 When it comes to legal, prescription stimulants, misuse can take several forms:12

  • Taking stimulants for non-therapeutic reasons (i.e., for the euphoric high).
  • Taking higher or more frequent doses of stimulants than prescribed.
  • Using prescription stimulants in a way they were not prescribed (e.g., crushing and snorting pills).
  • Taking prescription stimulants that are prescribed to someone else.

Some signs a person may be misusing prescription or illegal stimulants include:8

  • Appearing abnormally euphoric or energetic.
  • Being extra sensitive to lights, sounds, and touch.
  • Irritability.
  • Panic.
  • Confusion.
  • Paranoia.
  • Repetitive, agitated actions such as scratching.
  • Behavior that becomes bizarre, aggressive, or violent.
  • Sudden weight loss.

What to Do If You Suspect Someone Is Abusing Stimulants

Someone suffering from a stimulant addiction is not experiencing a failure of willpower but rather a chronic brain disorder for which professional treatment is often necessary.13,14 It’s important to avoid feeling like you alone can fix the problem for someone else.15 Instead, you can encourage your loved one to take steps toward seeking help.15

Consider the best way to provide encouragement to someone who is struggling. There is no evidence that confrontational “interventions” like those you may see on TV can help someone achieve long-term sobriety. This approach also has the possibility of backfiring or even erupting into violence.15

Often, individuals are more receptive to advice or statements from specialists than they are from family and friends, so providing them with resources and information or providing incentives for them to visit or doctor or addiction specialist may be helpful.15

If your loved one decides to get treatment, the support of friends and family during and after rehabilitation can make a big difference. Facilitating a positive network and being a champion for their recovery can help them prevent relapse.16

Detox & Treatment

Stimulant Addiction Treatment

It is very possible to recover from a stimulant use disorder with professional care and support.20 Treatment plans look different for everyone, but often addiction treatment involves a period of detox followed by inpatient or outpatient rehabilitation.

Stimulant Withdrawal and Detox

The prospect of going through withdrawal may deter someone from starting treatment.15 It is true that stimulant withdrawal—while seldom life-threatening—can be very unpleasant. Symptoms like depression, fatigue, and insomnia can spur those attempting to quit back to stimulants for relief. 1 Depression during and after withdrawal may range from mild to severe and can last for several weeks. During this time, a person is at increased risk of suicide. 8

Do I Need Medical Detox for Stimulants?

There are no medications specifically approved to treat stimulant withdrawal, and inpatient medical detox is not typically necessary to manage the physical symptoms of withdrawal from stimulants only.17 However, a supervised medical detox may be beneficial for those who are using other drugs, such as alcohol or benzodiazepines, in combination with stimulants.17 For those in detox for stimulants and other drugs, certain OTC and Rx medications may be used to combat specific stimulant withdrawal symptoms, and any concerning medical or psychiatric complications that arise can be dealt with immediately by medical staff.1

Clinical Treatment for Stimulant Addiction

While detox is a necessary first step in treatment for many, it does little to help someone achieve long-term sobriety. Addiction is a chronic brain disease and lasting recovery requires building the skills needed to recognize and avoid situations that threaten their sobriety and overcome the thought and behavioral patterns that may lead them to relapse or return to stimulant use.8,20

Effective rehabilitation for stimulant addiction is grounded in behavioral therapy. Treatment programs may utilize several different therapy types, which may include:

  • Contingency management. By incentivizing positive behaviors with small, tangible rewards, contingency management works to correct unhealthy patterns, foster short- and long-term goal planning, and promote the growth of healthy habits.8,18
  • Cognitive-behavioral treatment (CBT). CBT helps patients build effective and safe coping strategies to avoid relapse back to stimulant use.19
  • The Matrix Model. The Matrix Model is a therapeutic strategy that draws on multiple treatment approaches including drug education, family therapy, 12-Step involvement and more. This model fosters a healthy, direct but non-confrontational relationship between patient and therapist and raises the patient’s self-esteem and motivation to stay in recovery.8,20

AdCare treatment centers offer medical detox, as well as both inpatient rehab and outpatient rehab in Massachusetts and Rhode Island and is covered by many major insurance companies.

Please fill out the HIPAA-compliant to see whether your insurer covers treatment at AdCare or call to speak with an admissions navigator.

Learn More About Addiction Treatment

New England Stimulant Rehab FAQs

What Drugs Are Stimulants?

Stimulants are a category of drugs that enhance brain activity, leading to increased alertness, attention, and energy. Common examples include amphetamines, such as Adderall and methamphetamine, as well as cocaine and caffeine. These substances can be prescribed for legitimate medical purposes, like treating ADHD or narcolepsy, but they are also notorious for their misuse in recreational contexts.

What Are the Signs of Stimulant Use?

Identifying stimulant use can be critical for early intervention. Common physical signs include increased heart rate, elevated blood pressure, and dilated pupils. Behavioral signs may encompass heightened energy levels, euphoria, excessive talking, and decreased appetite. In more severe cases, psychotic symptoms such as paranoia or hallucinations may arise.

What Are the Dangers of Stimulants?

While stimulants can be beneficial when used appropriately, they carry significant risks. Prolonged use can lead to addiction, cardiovascular issues like heart attack or stroke, respiratory problems, and even neurological damage. The risk of overdose is a serious concern, especially with illicit stimulants, leading to potentially life-threatening situations.

Do Stimulants Cause Heart Problems?

Yes, stimulants can have serious effects on the cardiovascular system. They can cause increased heart rate and blood pressure, which elevate the risk of developing heart disease or suffering from acute events like heart attacks. This risk is heightened in individuals with pre-existing heart conditions or those engaging in high-stress activities while using stimulants.

What Does a Stimulant Rehab Entail?

Rehab for stimulant addiction typically includes a combination of detoxification, therapy, and support groups. The detox phase focuses on safely managing withdrawal symptoms under medical supervision. Behavioral therapies, such as cognitive-behavioral therapy (CBT), help individuals understand the root causes of their addiction and develop coping strategies. Ongoing support, including group therapy, encourages shared experiences and accountability.

How Do Stimulants Affect the Body?

Stimulants exert a range of effects on the body, primarily by increasing the production of neurotransmitters like dopamine and norepinephrine. This leads to heightened alertness and energy levels. However, they can also cause physical side effects like insomnia, decreased appetite, nausea, and muscle tension. Long-term use can result in more severe health issues, including weight loss and nutritional deficiencies.

While there is no FDA-approved treatment for stimulants, behavioral treatments such as contingency management, CBT and individual counseling can be useful for appropriate patients.

How Do Stimulants Affect the Brain?

Stimulants can significantly alter brain function by promoting the release of feel-good neurotransmitters, which can create a cycle of increased usage as individuals chase the euphoric feelings. Chronic use alters brain pathways and can lead to significant changes in mood, behavior, and cognition. Over time, this dependency can impair overall cognitive function and emotional regulation, making recovery challenging.

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